A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6cc08492c Click here for additional data file.

Another step toward DNA selective targeting: NiII and CuII complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes† †Electronic supplementary information (ESI) available. CCDC 1451694–1451696. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6dt00648e Click here for additional data file. Click here for additional data file.

DNA G-rich sequences are able to form four-stranded structures organized in stacked guanine tetrads. These structures, called G-quadruplexes, were found to have an important role in the regulation of oncogenes expression and became, for such a reason, appealing targets for anticancer drugs. Aiming at finding selective G-quadruplex binders, we have designed, synthesized and characterized a new w...

Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates† †Electronic supplementary information (ESI) available. CCDC 1521048–1521050. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc05354h Click here for additional data file. Click here for additional data file.

Exceptional time response, stability and selectivity in doubly-activated phenyl selenium-based glutathione-selective platform† †Electronic supplementary information (ESI) available: 1H, 13C, 77Se and 2D NMR, HRMS spectra of compounds, details of the synthetic procedure, additional fluorescent spectra, confocal microscopy image, DFT calculation data, live imaging movie. See DOI: 10.1039/c5sc02090e Click here for additional data file. Click here for additional data file.

Unravelling the effect of temperature on viscosity-sensitive fluorescent molecular rotors† †Electronic supplementary information (ESI) available: Additional spectroscopic and imaging data. See DOI: 10.1039/c5sc02248g Click here for additional data file.

Reversible quantitative guest sensing via spin crossover of an iron(ii) triazole† †Electronic supplementary information (ESI) available: Synthetic details, NMR spectra, instrumentation, plus additional structural, magnetic and TGA information and diagrams. CCDC 1434103 and 1434104. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc04583e Click here for additional data file. Click here for additional data file.